ABSTRACT
Aim: To evaluate women for precancerous and cancerouslesions of the cervix using the Pap smear test with specialreference to their correlation with age and clinical profile.Materials and Methods: This is a retrospective studyconducted at cytopathology section of Department ofPathology at Jawaharlal Nehru Medical College, Ajmer. 550smears were studied ranging from 18-90 year age group over aperiod of five months from July 2018 to November 2018. Theentire cervical smear received during this period were included.Results: A total of 550 cases were screened. There were 485(88.18%) abnormal pap smear with 43(7.81%) normal papcases and 22 (4%) cases were inadequate for evaluation. Outof 485 abnormal cases 337(69.48%) showed inflammation,8(1.64%) cases of atrophic smear, 5(1.03%) cases of ASCUS,3 (0.61%) cases of HSIL, 6 (1.23%) cases of LSIL, 3 (0.61%)cases of candida, 101 (20.82%) cases of bacterial vaginosis, 1(0.20%) case of erosion cervix, 2 (0.41%) cases of prolapse, 2(0.41%) cases of mild to moderate dysplasia, 5(1.03%) casesof reactive atypia, 1 (0.20%) case of intraepithelial neoplasm, 1(0.20%) case of atypical glandular cell, 6 (1.23%) cases ofmoderate to well differentiated SCC and 1 (0.20%) case ofchronic granulomatous disease were seen.Conclusion: Women between age group 30-49 years aremostly affected by pre-cancerous lesion. Every woman in thisage group should undergo Pap test at least once in her life.Timely screening of pre-invasive lesion allow prevention frominvasive cervical cancer.
ABSTRACT
Background: There is a wide spectrum of salivary gland lesions with morphological and clinical diversity which makes it a difficult task for histopathological interpretation. Tumours of salivary glands are uncommon accounting for 3-10% of the total tumors of head and neck region and less than one percent of all tumours. The aim of this study was to recognize various histomorphological patterns of salivary gland lesions, their frequency, age, gender and site wise distribution.Methods: This study was carried out from June 2015 to May 2018 in the department of Pathology, JLN Medical College and associated Group of Hospitals, Ajmer. Total 121 cases of salivary gland lesions were included. Specimens were processed and stained by Hematoxylin and Eosin stain followed by histopathological examination.Results: Out of total 121 cases, 43.8% were non-neoplastic and 56.2% were neoplastic. In non-neoplastic lesions predominant was chronic sialadenitis (50.9%) followed by mucocele (28.3%) which commonly seen in submandibular gland (47.17%). Among neoplastic cases, 79.4% were benign and 20.6% were malignant lesions. Neoplastic lesions commonly were seen in parotid (75%). Pleomorphic adenoma was the commonest benign tumour (81.4%). Mucoepidermoid carcinoma was the most common malignant salivary tumour. Benign tumours were common in third and fourth decades, whereas malignant tumours were more common in fifth and sixth decades. Male predominance was seen in overall salivary gland lesions.Conclusions: Histopathological examination is mandatory in the diagnosis of salivary gland lesions because of their wide spectrum of histomorphology.